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Some authors recommend anatomopathological examination for diagnostic confirmation, although others sustain that the diagnosis is only clinical and follow-up is necessary to investigate changes in size, shape, and color of the lesion.2,4 Although the number of documented cases allows no definitive conclusions, a clinical diagnosis of congenital melanotic macule of the tongue should be considered in the presence of the following characteristics: single or multiple lingual melanotic lesions, presence of a macular lesion at birth with proportional growth, and absence of family history of systemic conditions associated with mucosal pigmentation.2 For acquired cases, lingual melanotic macules, although rare, should be considered in the differential diagnosis of pigmented lesions of the oral mucosa

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Microbiol 32 , 884892

L-methionine and L-carnitine contained in the bolus improve energy processes and reduce fatty liver disease.

By combining the UV absorber PNA (PNA/butyric acid), which enhances the lipid reaction, with the protonator butyric acid, Ham et al

Serotonin levels, pain threshold, and fibromyalgia symptoms in the general population