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This activity-driven refinement is crucial during critical periods windows of heightened plasticity in childhood when sensory systems and cognitive functions are tuned

Meta-analysis The included studies showed substantial heterogeneity (I 2 = 99.6%, p 0.05), supporting the conclusion of comparable efficacy and the lack of a clear doseresponse relationship

Grannemann, Madhukar H
What is GHK-Cu and How Does it Interact with Skin

Future studies directly assessing receptor trafficking and internalization will be necessary to determine how these signaling profiles translate to receptor regulation and downstream cellular responses
