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The GDH enzymes identified in prokaryotes usually function with either NADP + (EC 1.4.1.4) or NAD + (EC 1.4.1.2) as co-factors whilst in higher eukaryotes the enzymes have dual co-factor specificity (EC 1.4.1.3)

[DOI] [PubMed] [Google Scholar] 166.Qureshi AA, Bradlow BA, Salser WA, Brace LD

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The importance of protein domain mutations in cancer therapy
