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Description
GHK has a physical structure similar to cimetidine which is often used to reduce pain in humans [51,52]
After virus entry in the CNS, it infects and replicates in microglia that acquire inflammatory phenotype, inducing a neurological damages [7]
Nat Rev Cardiol 17:773789
Typical supplementation involves 5001000 mL of polyphenol-rich pomegranate juice (often divided into multiple doses) or standardized extracts, with at least 5001000 mg administered daily [395,396,399403]
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A key finding was the upregulation of CHAC1 expression by DHA, which was mediated through the UPR pathways
