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Besides, Enterobacter aerogenes ZDY01 and Lactobacillus casei have also been shown to reduce circulating TMAO levels in murine model (Qiu et al., 2017

These researchers also showed that TMAO could only be produced in mice and people after bacteria in their intestines first metabolized the L-carnitine into trimethylamine (TMA)

L-Carnitine is a quaternary ammonium zwitterion with the chemical name (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate

Metabolic Considerations in Atrial Fibrillation- Mechanistic Insights and Therapeutic Opportunities

44 However, this effect of 3,3-dimethyl-1-butanol was not observed in the human colon model

aging-related blunted ketone utilization (Stroke Preclinical Assessment Network, SPAN trial: 60% lower -hydroxybutyrate uptake) [47, 48, 255]
