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The subsequent genetic mapping and eventual cloning of at least four homologous loci in humans has since demonstrated that these genes are responsible for the etiology and pathology of the Hermansky Pudlak Syndrome of human patients (Suzuki 2001

Experiments were done in triplicate

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What the potency comparisons actually showed In the classic anabolic studies, IGF analogs with reduced IGFBP binding including Long R3 IGF-1 produced greater nitrogen retention, greater gut and organ growth, and more pronounced anabolic responses than equimolar native IGF-1 in rodents, particularly in catabolic states such as dexamethasone treatment or dietary restriction

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