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doi: 10.1002/jemt.23390, PMID: [DOI] [PubMed] [Google Scholar] Fleming A

doi: 10.1021/acs.est.6b04140 18 LauraRMarcosRHernndezA

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Studies in animal models of renal insufficiency have demonstrated that GH or work overload-induced upregulation of IGF-1 expression in the skeletal muscle is partially reduced in animals with renal insufficiency.138 In the same way, a complementary study has shown that IGF-1, IGF-2 and IGF-1 receptor gene expressions are reduced in skeletal muscle from patients treated with hemodialysis as compare with normal control participant