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595,596,597,598 AFB1 causes human HCC by forming a 249Ser mutation in p53

Targeted and Other Testing: Occasionally, specific groups are targeted for additional testing

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Additionally, PGD 2 is metabolized by dehydrogenase to 15-keto-PGD 2 , which is further metabolized by 15-keto-PG-13-reductase to 13,14-dihydro-15-keto-PGD 2

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Despite using a similar cast of players, mtDNA replication is distinct from nuclear replication in many ways, including the fact that mtDNA replication occurs not only in dividing cells, but also in post-mitotic tissues and across all stages of the cell cycle