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Antiviral activity of phenformin in vivo Given that phenformin is an established drug in humans with known pharmacokinetics and safety profiles, that is hence readily available, we further evaluated the in vivo antiviral potential of phenformin against SARS-CoV-2 in a Golden Syrian hamster model of infection (Fig

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In neurons, glutamine serves as a precursor for the synthesis of active neurotransmitters, such as glutamate or GABA, which are packed inside vesicles to be released again during synaptic transmission [82,84,85]

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Cancer Res (2019) 79(6):122638