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Structure-activity Relationship of 39 Analogs of Laetispicine with Antidepressant Properties

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The glucosinolate glucoraphanin of broccoli sprouts interacts with myrosinase to produce the phytochemical sulforaphane (SFN) (Figure 6)

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Group V (VCO) was given CCl 4 and VCO (15 mL/kg p.o.) for 7 days

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NAC group (rats were injected intraperitoneally with MTX on day 7 plus NAC 500 mg/kg/day throughout the experiment by oral gavage, plus Kolliphor EL from day 1- day 10) (Li et al., 2018

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