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Peptide therapy is considered to be a very safe form of treatment, with minimal side effects

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In the present study, a well established rat model of periodontitis was utilized, which involves a ligature around the cervix of the mandibular first molar tooth (9, 10)

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Indeed, in both studies, the highest frequency of TEAEs was in the normal function groups, possibly owing to the smaller sample sizes in the more severe impairment groups, or alternatively because participants with more serious health concerns, such as those with severe renal or hepatic impairment, may be less likely to notice or report mild or moderate TEAEs, as observed in populations with cancer [21]