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TB-500 is also studied for its anti-inflammatory properties via TLR4/MyD88 pathway modulation and its role in reducing apoptosis in neural and cardiac tissue

Additionally, studies have pointed to the effect of BH4 inhibiting ferroptosis in T cells, and when the rate-limiting enzyme GCH1 of BH4 is deficient, it will inhibit the proliferation of T cells (159) ( Figure 3 )

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