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176 Additionally, oxidative stress can trigger cellular apoptosis and inflammatory responses

In particular, the recommended intake of vitamin B1 (thiamin) may be insufficient for a significant portion of the Western population

I think it can be used in conjunction but should not be sold as a quick fix for things like patella tendinopathies, meniscus tears etc

Transcriptional repression of atherogenic inflammation: modulation by PPARdelta

doi: 10.1038/aja.2008.32

Individuals who take vitamin C in supplement form are at greater risk of consuming too much of it and experiencing side effects, the most common of which are digestive issues