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Murphy PJ, Myers BL, Badia P
I've seen more of positive results than negative ones

Choline is actively transported across the placenta, leading to fetal plasma choline levels six to seven times higher than maternal blood levels, and amniotic fluid concentrations nearly ten times higher (35)

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Holt DA, Levy MA, Metcalf BW
When co-cultured with endothelial cells, endothelial-derived TGF- can induce the switching of VSMCs into a secretory phenotype by regulating the phosphoinositide 3-kinase/AKT signaling pathway (181, 182)