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Curcumin-treated cells showed elevated ROS, MDA and Fe2+ levels, decreased SOD, GSH and GPX4 levels, and increased nuclear NRF2 level and nuclear translocation, and HMOX1 expression, suggesting that curcumin activated the NRF2/HMOX1 pathway to promote ferroptosis, thereby inhibiting lung cancer cell malignant progression

So being sedentary as Im saying, its low cardiorespiratory fitness I guess its not exactly correct, Im stretching it a little bit, but cardiorespiratory fitness is a marker of fitness

Neutrophil apoptosis: A marker of disease severity in sepsis and sepsis-induced acute respiratory distress syndrome

Association study of HIF-1 rs11549465 and VEGF rs3025039 genetic variants with diabetic retinopathy in Egyptian patients: crosslinks with angiogenic, inflammatory, and anti-inflammatory markers