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The cumulative effect isnt just additive it can be exponential

Glutathione-dependent enzyme activities of peripheral blood mononuclear cells decrease during the winter season compared with the summer in normal-weight and severely obese adolescents

Blood 108(11):292b, 2006

Hamilton Poland

K.SpiliotisB

This article probes the mechanism of the thiol-disulphide oxidoreductase DsbD and provides an elegant example of the intra-protein transfer of disulphide bonds that seems be important in the function of several proteins involved in cellular protein oxidation and reduction
