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It is likely that the larger number of statistically significant changes to the microbiome observed in the groups switched from WD to LD reflects their more numerous exposures to different diets, longitudinal changes in dietary exposure, the stress associated with diet switch, the negative energy state achieved by treatment and/or diet-driven weight loss, or a combination of these factors, but it may also be related to differences in terminal body weight and fat mass since both adiposity and diet composition have been shown to modulate the mouse gut microbiome profile

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Repeat Daily Once or twice a day

Day 5 Floating Islands of Uros and Taquile After breakfast at the hotel, we begin the excursion with a transfer to the dock to board the vessel heading to the Floating Islands of the Uros , located in the National Reserve of Lake Titicaca

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