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Neuronal NOS (nNOS/NOS1) has emerging evidence suggesting a role in neuronal-like signaling within the tumor microenvironment (57) demonstrated that mtNOS1 suppresses cisplatin-induced mitochondrial superoxide accumulation and apoptosis in colon cancer cells by enhancing SIRT3 activity, which stabilizes SOD2a key antioxidant enzyme

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Countries such as Japan, South Korea, and China are emerging as key leaders, leveraging advanced bio-fermentation technologies, cosmetic innovation, and d!etary supplement adoption to support consumer wellness and healthcare

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