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Mechanisms involved are thought to include tracheal microaspiration of acid stimulating bronchospasm 30 and increased airway hyper-reactivity associated with acid reflux into the lower esophagus

Pregnancy Safety Registries: Ongoing pharmacovigilance and pregnancy exposure registries are necessary to define teratogenic risk and optimal discontinuation intervals

Mercer, D.K., Robertson, J.C., Miller, L., Stewart, C.S., and ONeil, D.A., Med

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