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Centers generally assess current stability and absence of recent hypoglycemia rather than specific hemoglobin A1c numbers

The complexity of the system is illustrated by findings that systemic salicylate-induced hyperactivity in the IC depends on nitric oxide signaling within that structure, which is known to mediate NMDA receptor signaling, indicating that interventions could target points in the signaling cascade upstream or downstream of the receptor itself (Olthof et al., 2022)

[DOI] [PubMed] [Google Scholar] Bar-Or D, Thomas GW, Rael LT, Lau EP, Winkler JV

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