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Evidence for a splanchnic sodium input monitor regulating renal sodium excretion in man
Tirzepatide, on the other hand, is a dual agonist, targeting both the GLP-1 and GIP receptors, offering enhanced glucose control and weight loss by combining the effects of both incretin hormones
Science 123 , 309314 (1956)
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It has been reported that only the exo-epoxide effectively interacts with DNA and was at least 500-fold more potent as a mutagen than the endo stereoisomer
doi: 10.1111/j.1432-1033.1993.tb18025.x
