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Current clinical practice emphasizes personalized treatment plans tailored to each patients predominant clinical manifestations
Many of these molecules are direct inhibitors (including 48C) that specifically target at lysine 907 in RNAse domain and this impairs RNA splicing (Sanches et al
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doi: 10.1016/j.freeradbiomed.2024.08.039 198 ZhuL.YuT.WangW.XuT.GengW.LiN.et al
Lancet Neurol 8 : 382397
