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Some users notice warming sensations near injection sites, possibly related to increased local blood flow from nitric oxide effects

JAMA Network Open full text iconFULL TEXTcontents iconCONTENTSfigure iconFIGURES / TABLESattach iconSUPPLEMENTAL CONTENTreferences iconREFERENCESrelated iconRELATEDcomments iconCOMMENTS Download PDF Comment Top of Article Key Points Abstract Introduction Methods Results Discussion Conclusions Article Information References Figure 1

Some high risk groups for vitamin B12 deficiency include: elderly people- often stomach acid production decreases with age individuals who have had intestinal surgery such as weight loss surgery or laparoscopies individuals with GI issues including celiac disease, IBD, IBS (MOST OF YOU!!!) those following a vegetarian or vegan diet- due to the lack of animal protein eaten (one of the main sources of B12) individuals with pernicious anemia- do not make intrinsic factor Notice how a fair amount of the high risk individuals are those with some sort of intestinal issue