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Our attempts to verify these phospho-sites in cells co-expressing ArfGAP1 with LRRK2 variants combined with mass spectrometry analysis of immunoprecipitated ArfGAP1 were unsuccessful, most likely due to the low abundance and/or compartment-specific localization of these LRRK2-specific phosphorylation sites for detection in whole cell extracts

Direct NAD+ research largely remains preclinical

[DOI] [PubMed] [Google Scholar] 28.Zhu YS, Cai LQ, You X, Cordero JJ, Huang Y, Imperato-McCinley J

The systemic side effects of weight gain, osteoporosis (thin bones), and increased blood pressure typically do not occur with steroid injections

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