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The upstream and downstream regulators of NLRP3 in APAP-induced liver injury are summarized in Tables 1 and 2

Activation of the CH bond in the -keto acid (or -imino acid) facilitates a ,-elimination reaction with the production of vinylglyoxylate (2-oxo-3-butenoic acid) (Eq

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4 Department of Natural and Life Sciences, Long Island University, Brooklyn, NY, 11201, USA Correspondence: Dong H Kwon, Department of Natural and Life Sciences, Long Island University, 1 University Plaza, Brooklyn, NY, 11201, USA, Tel +1 718 780 4098, Fax +1 718 488 1465, Email [email protected] Abstract: Antibiotic resistance has spread globally among bacterial pathogens, becoming a significant challenge to public health

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