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Li L, Li WJ, Zheng XR, Liu QL, Du Q, Lai YJ, et al
doi: 10.1038/s41531-022-00355-2 193 GuJBarreraJYunYMurphySKBeachTGWoltjerRLet al
Grace, K
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Taken together, our results demonstrate a synthetic lethal approach to exploit the glucose addiction phenotype in cancer cells
By implementing sample multiplexing and a redesigned lysine-targeting probe, we streamline a quantitative activity-based protein profiling, enabling the direct mapping of global reactivity and ligandability of proteinaceous lysines in human cells
