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doi: 10.1074/jbc.M111.253914 28 KlotzCZieglerTFigueiredoASRauschSHepworthMRObsivacNet al

Unfortunately these increases in HGF are not maintained with disease progression, and the hippocampal HGF/Met system appears to be down regulated in AD patients [95]

10.4331/wjbc.v9.i1.1 [DOI] [PMC free article] [PubMed] [Google Scholar] 60.Wang J, He W, Tsai PJ, Chen PH, Ye M, Guo J, et al

10.4103/ijo.IJO_1921_21 82 JiH.YangY.LuY.KongX.YangG.LiuJ.et al (2023)

Multiple studies have demonstrated the robust potential of the Dsup protein to protect biomedical cells from DNA damage caused by radiation and oxidative stress, as well as to shield healthy tissues during cancer therapy

When restoration fails, UPR switches in to an alternative mode and turns on the apoptotic signaling pathway in the -cells
