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PD patients commonly show cognitive deficiencies when glutamate levels rise above normal levels (Pourhamzeh et al., 2022)

Nat Cell Biol 2015;17:1556-68

This functional disorder not only disrupts the normal regulatory mechanisms of blood vessels but also leads to increased blood pressure, arterial stiffness, and remodeling of small arteries, ultimately resulting in multi-organ damage (Boutouyrie et al., 2021

The activity of AChE was presented as mol/min/g of brain tissue

Never double-dose to compensate the additive hypoglycemia risk outweighs any signaling benefit

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