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Investments in research capacity-building, shared protocols, regional biobanking, and data analysis platforms are necessary to ensure that scientific innovation in neuroprotection has truly global reach and impact [633]

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Although rare, adverse effects of high-dose vitamin B12 have been reported, including allergic reactions such as fever, rash, itching, hot flushes, dizziness, and nausea, across all cobalamin forms and administration routes ( Intramuscular (IM) injection is the most invasive and costly administration method, requiring trained personnel and clinical visits

It contains a bacteriostatic preservative that helps inhibit the growth of bacteria after the vial has been opened, making it suitable for repeated laboratory use under controlled research conditions

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