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Doses above 1.5mg produce this effect in most subjects regardless of receptor sensitivity

Chromosomal localization of lipolytic enzymes in the mouse: pancreatic lipase, colipase, hormone-sensitive lipase, hepatic lipase, and carboxyl ester lipase

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The aim of the study was clearly explained to all the study participants and a written informed consent was obtained

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Indeed, IDH1 inhibition or glutamine starvation in MYC-overexpressing cells decreased KG abundance (Extended Data Fig