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Serum CRP and ESR as an inflammatory agent, serum lactate dehydrogenase (LDH) as a marker of cell injury, total oxidative stress (TOS), and total antioxidant capacity (TAC) as an oxidative stress biomarker will be measured as our primary outcomes

Under experimental conditions, it has been demonstrated that DPN is provoked by multiple interactive pathogenic mechanisms, including oxidative stress, protein kinase C and microvascular disease (3)

Modalit duso: assumere 3 pastiglie una o due volte al giorno, anche in ununica somministrazione (6 pastiglie)

Hamed SA, Abdella MM

J Inherit Metab Dis 30(6):865879