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2019;708:1420 DOI: 10.1016/j.gene.2019.05.023 34

doi: 10.3390/biomedicines9091194

M., Wang Q., Raghu H., Mao R., Lindstrom T

Flavonoids as nutraceuticals: A review

however, the relapse rate is higher ( ATM or CHEK2 mutations are usually estrogen receptor positive (ER+) and less aggressive ( 10% of breast cancer is inherited, developments in molecular oncology and genetic screening technologies are allowing us to understand the role of genetic risk and develop personalized preventive and therapeutic plans for individual patients harboring pathogenic mutations ( 2.3 Lifestyle factors Lifestyle factors play an important and crucial role in shaping individual risk in developing breast cancer ( 2.4 Environmental factors Other than genetic, hormonal, and lifestyle risk factors, environmental exposures have emerged as another significant contributor to breast cancer risk ( 2.5 Reproductive, nutritional, ethnic and sociocultural factors Dietary patterns play a critical role in modulating the risk of breast cancer occurrence