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204 In liver cancer, upregulating the crotonylation level by knocking down HDACs or adding HDAC inhibitors could inhibit hepatoma cell motility and proliferation

Boosts Metabolism: By supporting fundamental metabolic processes, NAD+ can help maintain a healthy weight and overall metabolic balance
It enhances fatty acid oxidation, lowers low-density lipoprotein (LDL) oxidation, downregulates DNL, improves insulin sensitivity, and inhibits NF-B signaling [80]
An excess of ROS production leads to a reduction in muscle resistance capacity that contributes to fatigue [125]

It is also commonly used orally or in I.V injection as a skin whitener, because of its ability to reduce melanin production
