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A study conducted in mice demonstrated that IL-6 is markedly elevated in individuals after hypercytokinemia was induced by peroxidized phospholipids and intrapulmonary acid

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Further study supported the antiinflammatory potential of bilirubin in the EAE model [64]

Astrocytes maintain their antioxidative functions through two primary mechanisms: the Nrf2keap1antioxidant response element (ARE) pathway and glutathione (GSH) synthesis

4 Role of anthocyanin in age-related diseases 4.1 Anthocyanins and neurodegenerative diseases Aging is the primary risk factor for neurodegenerative diseases, particularly Alzheimers Disease (AD), Parkinsons Disease (PD), and Amyotrophic Lateral Sclerosis (ALS), all of which become more prevalent with age (36)