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The IL-17 secreted by these cells binds to IL-17 receptors (IL-17Rs) expressed in midbrain neurons, inducing neuronal death through the upregulation of NF-B and downstream signaling pathways, as demonstrated in human iPSC-derived neuronal models

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The catalytic degradation of H 2 O 2 by NPs was further confirmed using a hydrogen peroxide assay kit (Fig

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