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J., Edwards, A

, Raoul P., Cintoni M., et al

Physiol Rev 96:117

As a result, immune cells such as TAMs, tumor-associated neutrophils (TANs), tumor-infiltrating T lymphocytes (TILs) and MDSCs can modulate cancer cachexia via the following mechanisms: (1) they impact key target organs such as skeletal muscle, adipose tissue and even the nervous system, inducing a cascade of pathological effects within these tissues through signal transduction mechanisms

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