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HIIT induces swift and substantial enhancements in both endothelial function and mitochondrial capacity, even with a reduced total exercise volume, thereby establishing it as a time-efficient strategy to enhance vascular responsiveness and oxidative metabolism among older populations (78, 79)

Not surprisingly, the production of ROS is a key factor in the etiology of several neurodegenerative diseases [18]

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Moreover, only 54% of patients in those economics have access to oral cysteamine therapy, and there is limited access to cysteamine eye drops, supportive therapies, and standard diagnostic and monitoring tools, all of which are essential for the prevention of disease progression and extended lifespan [159]