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Abstract The intestinal wall is a selectively permeable barrier between the content of the intestinal lumen and the internal environment of the body

Likewise, decreased gene expression of Egr was evident at 24 h in the inferior caval vein, Vegfr expression was decreased at 1 h and 24 h in all vessels, and Plc gene expression was decreased at 24 h in the inferior caval vein

This sublingual-like absorption route theoretically allows the peptide to enter the bloodstream more directly, avoiding first-pass metabolism in the liver and enzymatic degradation in the stomach