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Lactobacillus amylovorus inhibits the TLR4 inflammatory signaling triggered by enterotoxigenic Escherichia coli via modulation of the negative regulators and involvement of TLR2 in intestinal Caco-2 cells and pig explants

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Altogether, these events result in neurodegeneration causing cerebral dysfunction, brain atrophy, and dementia [20,144,146], and emphasize that biochemical decompensation resulting from VitB12 insufficiency is not the sole contributor to demyelination