glutathione s-transferase gsts catalyze the conjugation Multifaceted Role of S-Transferases in Health and Disease General reaction catalyzed by glutathione

Dutchak, P

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

In other cases, the reactive forms of oxygen (singlet oxygen, the superoxide and hydroxyl radicals, hydrogen peroxide), that are not coped with by the natural detoxifying mechanisms, can react with biological structures and impair their physiological function

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, protein kinase C (PKC) and mitogen-activated protein kinase (MAPK)), and metabolic enzymes

To get around this problem, therapeutic doses of glutathione are administered intravenously