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Quantitative analysis of oxygen consumption demonstrates a 45% reduction in oxidative phosphorylation capacity, accompanied by dysregulated acyl-CoA oxidation and accumulation of oxidative stress markers, specifically 4-hydroxynonenal adducts within subcutaneous adipose deposits (87)
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In transgenic animal models of PD, treatment with resveratrol improves motor and cognitive functions, decreases neuroinflammation, and directly prevents S aggregation (Zhang et al., 2018)
J Exp Med 200(3):377389 Kang H-R, Cho SJ, Lee CG, Homer RJ, Elias JA (2007) Transforming growth factor (TGF)-1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, Bid-activated pathway that involves matrix metalloproteinase-12
Protective role of sirtuin3 (SIRT3) in oxidative stress mediated by hepatitis B virus X protein expression
