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In addition, since mitochondrial dysfunction leads to the activation of apoptosis, SIRT1 can directly regulate the apoptotic process by modulating acetylation of PGC-1 (Zhang et al., 2019)
A GSTM2 overexpression vector was transfected into mice fed MCDD for 2 weeks, which was then changed to a chow diet (Supplementary Fig
10.1007/s13238-020-00789-5 52 KraftV
PLoS Biol 13(8):e1002226
As to iron, which is an important condition for ferroptosis, its dietary intake was positively associated with endometrial cancer risk (adjusted OR = 1.9
doi: 10.5005/jp-journals-10082-03106
