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Enhancing Synaptic Plasticity (top left, blue): Modulation of AMPA and NMDA receptors boosts excitatory synaptic transmission and long-term potentiation (LTP)

Biologia 68:10721078 Patra A, Mandal A, Samanta A, Mahapatra TD, Mandal S et al (2014) Therapeutic effect of Streptococcus thermophilus (MTCC 1938) on acetaminophen induced uremia in experimental rats

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This coordinates the regulation of key enzymes in lipid metabolism: it inhibits the expression of lipogenic enzymes (FAS and ACC) while upregulating the rate-limiting enzyme for fatty acid -oxidation, CPT1A, thus correcting lipid metabolic imbalance, reducing hepatic lipid deposition, and improving insulin resistance from the metabolic source (72)

Curr Neuropharmacol 19(7):10191037 Early increasing-intensity Treadmill exercise reduces neuropathic pain by preventing nociceptor collateral sprouting and disruption of chloride cotransporters homeostasis after peripheral nerve injury