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HR-MS is a preferred LC/MS platform for a drug metabolism lab where metabolite identification is its major task, while quantitative analysis in discovery pharmacokinetic and in vitro metabolism studies is performed occasionally [44, 45]

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Clinical trials evaluate different inhibitors and targets of KRAS, with some inhibitors having already passed the initial clinical trial phase, while others are currently in phase 2 or 3 trials

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S.HobanK.ModlaS.et al (2015)
