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Virus-induced metabolic disordernew onset diabetes T2DM is a progressive metabolic disorder due to insulin resistance with underlying chronic inflammation as well as endothelial and -cell dysfunction 744

Makhoul E, El Mir J, Loutfi T, Assaf Y

Given that SASP factors influence these(Campisi, 2013), it will be particularly interesting to determine whether FOXO4-DRI affects those p53-wt cancer cells that have adopted a more migratory and stem-like state due to reprogramming by chronic SASP exposure
Nasrallah F, Kraoua I, Joncquel-Chevalier Curt M, Bout MA, Taieb SH, Feki M, Khouja N, Briand G, Kaabachi N

It penetrates cells to exert direct anti-inflammatory effects
