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Real-world data : Prospective cohorts (n=117) demonstrated sustained benefits over a median 2.0 years, with increased outdoor time (+6.1 hours/week) and improved quality of life (+14%)

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These compounds are under tight biosynthetic control, with short and long negative feedback loops that regulate the secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH) by the pituitary and gonadotropin releasing hormone (GnRH) by the hypothalamus
