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Folate and DNA methylation: a review of molecular mechanisms and the evidence for folates role

CYTOSOLIC AND MITOCHONDRIAL ONE-CARBON METABOLISM GENERATES NADPH One-carbon metabolism integrates the amino acids serine and glycine into the folate and methionine cycles that participate in many diverse biological outputs, including nucleotide synthesis (see Chandel 2020c) and methylation reactions involved in epigenetics (see Chandel 2020d)

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10.1038/nri1312 160 LapougeK.SmithS.WalkerP.GamblinS.SmerdonS.RittingerK

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