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Nora Volkow, director of the National Institute on Drug Abuse (NIDA), and many addiction researchers and clinicians, view addiction as a brain disease triggered by many genetic, environmental, and social factors

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Intrinsic ADE is distinct from extrinsic ADE, because intrinsic ADE leads to an increased number of infected cells

This misbalance in the antioxidant activities was accompanied by the elevation of TBARS and protein carbonyls levels (Figures 2C, D)

Rather than finding a single best antioxidant target to support the regulation of age-related decline in redox state, we explore an activator of the cells balanced antioxidant/oxidative redox response, the transcription factor Nrf2 (nuclear erythroid factor-like 2)