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However, in cases of disease, injuries, or another disabling factors, the production of thyroid hormones will be compromised

Gerszberg, A., Hnatuszko-Konka, K., Kowalczyk, T

Destabilizing mutations facilitate this initial transition, and the increased rate of conversion to a pathological state likely contributes to the earlier age of onset compared with wild-type TTR amyloidosis

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It usually involves pill organizers or plastic bags, and me forgetting which capsule is which