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Specialized toxicology research shows no embryo-fetal developmental toxicity, no genetic mutagenicity in bacterial and mammalian cell assays, and no adverse reproductive effects in animal models

(2021) 39: 24056.e11

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By contrast, reactive astrocytes modulate Ca 2+ signaling by overexpressing calcineurin, a Ca 2+ -dependent phosphatase that activates inflammation-related genes

doi: 10.2174/1566524033479582

However, this should not be misinterpreted as indicating that CD8 + Teff cells have low oxidative TCA cycle activity
